Glossary

Model

In DendroTweaks, a computational representation of a neuron that includes its morphological structure, membrane properties, and simulation parameters necessary for numerical simulation.

Tree graph

A hierarchical graph structure where nodes are connected by edges, with no cycles and a single path between any two nodes.

Node

The fundamental unit of which graphs are formed.

Edge

A connection between two nodes in a graph.

Tree traversal

An algorithmic process of visiting each node in a tree graph exactly once.

Reconstruction

A digital representation of a neuron’s three-dimensional morphology, composed of interconnected points with spatial coordinates.

SWC file

A standard text-based file format for storing neuronal morphology data, where each line represents a point with its type, coordinates, radius, and parent point index.

Point

A discrete location in 3D space representing a specific position in a neuronal reconstruction, defined by x, y, z coordinates and associated properties.

Section

A continuous unbranched segment of a neuron between points of topological change (bifurcations).

Domain

A collection of sections sharing common morphological or physiological characteristics, typically corresponding to parts of a neuron such as soma, dendrites, axon, etc.

Segmentation

The process of dividing a section into smaller segments to discretize the spatial domain for numerical simulation.

Segment

A small subunit of a section resulting from the segmentation process, used to approximate the spatial properties of a neuron.

Segment Group

A collection of segments selected based on specific criteria such as domain, diameter, or distance.

Membrane mechanism

A mathematical model describing the electrical properties of a neuronal membrane, such as ion channels and pumps.

MOD file

A NEURON-specific file containing the implementation of membrane mechanisms, defining their mathematical equations and computational behavior.

Parameter

A quantitative variable describing specific neuronal properties, such as membrane capacitance, ion channel conductance, or other physiological characteristics.

Distribution

A mathematical function that assigns parameter values across neuronal structures based on spatial or morphological relationships.

Synapse

A specialized junction enabling signal transmission between neurons, represented computationally as a point of conductance and kinetic changes.

Population

In DendroTweaks, a group of “virtual” neurons that form synapses on the postsynaptic neuron (the model). The synapses in a population share the same kinetic and activation properties.