Introduction¶

Welcome to DendroTweaks documentation!

DendroTweaks is a Python toolbox designed to facilitate the creation and validation of single-cell biophysical neuronal models.

The toolbox is available both as a standalone Python package and as a web-based application.

Online platform	https://dendrotweaks.dendrites.gr
PyPI project	https://pypi.org/project/dendrotweaks
Python package source code	https://github.com/Poirazi-Lab/DendroTweaks
Web application source code	https://github.com/Poirazi-Lab/DendroTweaksApp

For a quick overview of the toolbox, including a video demonstration, you can visit our e-poster presented at the FENS Forum 2024 in Vienna.

To learn more about the toolbox, you can read our publication in eLife.

Citation

Roman Makarov, Spyridon Chavlis, Panayiota Poirazi (2025) DendroTweaks, an interactive approach for unraveling dendritic dynamics eLife 13:RP103324 https://doi.org/10.7554/eLife.103324.3

If you find DendroTweaks helpful for building your models, please consider citing our work.

@article {Makarov2025,
   article_type = {journal},
   title = {DendroTweaks, an interactive approach for unraveling dendritic dynamics},
   author = {Makarov, Roman and Chavlis, Spyridon and Poirazi, Panayiota},
   volume = 13,
   year = 2025,
   month = {dec},
   pub_date = {2025-12-23},
   pages = {RP103324},
   citation = {eLife 2025;13:RP103324},
   doi = {10.7554/eLife.103324},
   url = {https://doi.org/10.7554/eLife.103324},
   journal = {eLife},
   issn = {2050-084X},
   publisher = {eLife Sciences Publications, Ltd},
}

Getting started:

Tutorials:

API Reference:

Useful resources: